Increased Stiffness Downregulates Focal Adhesion Kinase Expression in Pancreatic Cancer Cells Cultured in 3D Self-Assembling Peptide Scaffolds

The focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that participates in integrin-mediated signal transduction and contributes to different biological processes, such as cell migration, survival, proliferation and angiogenesis. Moreover, FAK can be activated by autophosphorylation at p...

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Detalles Bibliográficos
Autores principales: Betriu, Nausika, Andreeva, Anna, Alonso, Anna, Semino, Carlos E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405295/
https://www.ncbi.nlm.nih.gov/pubmed/36009384
http://dx.doi.org/10.3390/biomedicines10081835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405295/
https://www.ncbi.nlm.nih.gov/pubmed/36009384
http://dx.doi.org/10.3390/biomedicines10081835

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