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Identification of Novel Inhibitor of Enoyl-Acyl Carrier Protein Reductase (InhA) Enzyme in Mycobacterium tuberculosis from Plant-Derived Metabolites: An In Silico Study

Mycobacterium tuberculosis (M.tb.) enoyl-acyl carrier protein (ACP) reductase (InhA) is validated as a useful target for tuberculosis therapy and is considered an attractive enzyme to drug discovery. This study aimed to identify the novel inhibitor of the InhA enzyme, a potential target of M.tb. inv...

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Detalles Bibliográficos
Autores principales: Singh, Kratika, Pandey, Niharika, Ahmad, Firoz, Upadhyay, Tarun Kumar, Islam, Mohammad Hayatul, Alshammari, Nawaf, Saeed, Mohd, Al-Keridis, Lamya Ahmed, Sharma, Rolee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405319/
https://www.ncbi.nlm.nih.gov/pubmed/36009907
http://dx.doi.org/10.3390/antibiotics11081038