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Intermittent Hypoxia-Induced Cardiomyocyte Death Is Mediated by HIF-1 Dependent MAM Disruption

Rationale: Intermittent hypoxia (IH) is one of the main features of sleep-disordered breathing (SDB). Recent findings indicate that hypoxia inducible factor-1 (HIF-1) promotes cardiomyocytes apoptosis during chronic IH, but the mechanisms involved remain to be elucidated. Here, we hypothesize that I...

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Detalles Bibliográficos
Autores principales: Moulin, Sophie, Thomas, Amandine, Wagner, Stefan, Arzt, Michael, Dubouchaud, Hervé, Lamarche, Frédéric, Bouyon, Sophie, Vial, Guillaume, Godin-Ribuot, Diane, Pépin, Jean-Louis, Arnaud, Claire, Belaidi, Elise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405320/
https://www.ncbi.nlm.nih.gov/pubmed/36009181
http://dx.doi.org/10.3390/antiox11081462