NPM1-Mutated Patient-Derived AML Cells Are More Vulnerable to Rac1 Inhibition

The prognosis of acute myeloid leukemia (AML) is poor, especially for the elderly population. Targeted therapy with small molecules may be a potential strategy to overcome chemoresistance and improve survival in AML. We investigated the inhibition of the signaling molecule ras-related C3 botulinum t...

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Detalles Bibliográficos
Autores principales: Hemsing, Anette Lodvir, Rye, Kristin Paulsen, Hatfield, Kimberley Joanne, Reikvam, Håkon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405324/
https://www.ncbi.nlm.nih.gov/pubmed/36009428
http://dx.doi.org/10.3390/biomedicines10081881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405324/
https://www.ncbi.nlm.nih.gov/pubmed/36009428
http://dx.doi.org/10.3390/biomedicines10081881

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