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PD-L1/pS6 in Circulating Tumor Cells (CTCs) during Osimertinib Treatment in Patients with Non-Small Cell Lung Cancer (NSCLC)

The PD-1/PD-L1 axis provides CTCs an escape route from the immune system. Phosphorylation of the ribosomal protein S6 is implicated in the same pathway, following mTOR activation. The aim of the study was to investigate the expression of PD-L1 and pS6 in CTCs from NSCLC patients under Osimertinib tr...

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Detalles Bibliográficos
Autores principales: Pantazaka, Evangelia, Ntzifa, Aliki, Roumeliotou, Argyro, Lianidou, Evi, Georgoulias, Vassilis, Kotsakis, Athanasios, Kallergi, Galatea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405335/
https://www.ncbi.nlm.nih.gov/pubmed/36009440
http://dx.doi.org/10.3390/biomedicines10081893