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Valve Endothelial Cell Exposure to High Levels of Flow Oscillations Exacerbates Valve Interstitial Cell Calcification

The aortic valve facilitates unidirectional blood flow to the systemic circulation between the left cardiac ventricle and the aorta. The valve’s biomechanical function relies on thin leaflets to adequately open and close over the cardiac cycle. A monolayer of valve endothelial cells (VECs) resides o...

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Detalles Bibliográficos
Autores principales: Hsu, Chia-Pei Denise, Tchir, Alexandra, Mirza, Asad, Chaparro, Daniel, Herrera, Raul E., Hutcheson, Joshua D., Ramaswamy, Sharan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405348/
https://www.ncbi.nlm.nih.gov/pubmed/36004918
http://dx.doi.org/10.3390/bioengineering9080393