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Primary-like Human Hepatocytes Genetically Engineered to Obtain Proliferation Competence as a Capable Application for Energy Metabolism Experiments in In Vitro Oncologic Liver Models

SIMPLE SUMMARY: Fatty liver disease is an increasing health concern in Westernized countries. A fatty liver can lead to hepatocellular carcinoma (HCC), a type of liver cancer arising from hepatocytes, the major cells of the liver. How HCC may develop from the fatty liver is not known, and good cellu...

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Detalles Bibliográficos
Autores principales: Scheffschick, Andrea, Babel, Jonas, Sperling, Sebastian, Nerusch, Julia, Herzog, Natalie, Seehofer, Daniel, Damm, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405410/
https://www.ncbi.nlm.nih.gov/pubmed/36009822
http://dx.doi.org/10.3390/biology11081195