The pharmacokinetic and pharmacodynamic properties and short-term outcome of a novel once-weekly PEGylated recombinant human growth hormone for children with growth hormone deficiency

OBJECTIVES: To investigate the pharmacokinetics (PK) and pharmacodynamics (PD) of Y-shape branched PEGylated recombinant human growth hormone (YPEG-rhGH) and evaluate its short-term efficacy and safety in children with growth hormone deficiency (GHD). METHODS: A total of 43 children with GHD from 12...

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Detalles Bibliográficos
Autores principales: Liang, Yan, Zhang, Cai, Wei, Haiyan, Du, Hongwei, Zhang, Gaixiu, Yang, Yu, Zhang, Hua, Gong, Haihong, Li, Pin, Song, Fuying, Xu, Zhuangjian, He, Ruoyi, Zhou, Weidong, Zheng, Heng, Sun, Li, Luo, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405430/
https://www.ncbi.nlm.nih.gov/pubmed/36034448
http://dx.doi.org/10.3389/fendo.2022.922304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405430/
https://www.ncbi.nlm.nih.gov/pubmed/36034448
http://dx.doi.org/10.3389/fendo.2022.922304

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