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Multiple Sclerosis: Enzymatic Cross Site-Specific Recognition and Hydrolysis of H2A Histone by IgGs against H2A, H1, H2B, H3 Histones, Myelin Basic Protein, and DNA

Histones have a paramount role in chromatin remodeling and gene transcription. Free histones are damage-associated molecules in the blood; administration of histones to animals drives systemic inflammatory and toxic effects. Myelin basic protein (MBP) is the most crucial component of the axon myelin...

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Detalles Bibliográficos
Autores principales: Nevinsky, Georgy A., Buneva, Valentina N., Dmitrienok, Pavel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405453/
https://www.ncbi.nlm.nih.gov/pubmed/36009424
http://dx.doi.org/10.3390/biomedicines10081876