Quercetin Attenuates Quinocetone-Induced Cell Apoptosis In Vitro by Activating the P38/Nrf2/HO-1 Pathway and Inhibiting the ROS/Mitochondrial Apoptotic Pathway

Quinocetone (QCT), a member of the quinoxaline 1,4-di-N-oxides (QdNOs) family, can cause genotoxicity and hepatotoxicity, however, the precise molecular mechanisms of QCT are unclear. This present study investigated the protective effect of quercetin on QCT-induced cytotoxicity and the underlying mo...

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Detalles Bibliográficos
Autores principales: Dai, Chongshan, Zhang, Qinzhi, Shen, Linjie, Sharma, Gaurav, Jiang, Haiyang, Wang, Zhanhui, Shen, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405464/
https://www.ncbi.nlm.nih.gov/pubmed/36009217
http://dx.doi.org/10.3390/antiox11081498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405464/
https://www.ncbi.nlm.nih.gov/pubmed/36009217
http://dx.doi.org/10.3390/antiox11081498

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