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Pre‐steady‐state kinetics and solvent isotope effects support the “billiard‐type” transport mechanism in Na (+)‐translocating pyrophosphatase

Membrane‐bound pyrophosphatase (mPPase) found in microbes and plants is a membrane H(+) pump that transports the H(+) ion generated in coupled pyrophosphate hydrolysis out of the cytoplasm. Certain bacterial and archaeal mPPases can in parallel transport Na(+) via a hypothetical “billiard‐type” mech...

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Detalles Bibliográficos
Autores principales: Malinen, Anssi M., Anashkin, Viktor A., Orlov, Victor N., Bogachev, Alexander V., Lahti, Reijo, Baykov, Alexander A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405524/
https://www.ncbi.nlm.nih.gov/pubmed/36040263
http://dx.doi.org/10.1002/pro.4394