Molecular Threat of Splicing Factor Mutations to Myeloid Malignancies and Potential Therapeutic Modulations

Splicing factors are frequently mutated in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). These mutations are presumed to contribute to oncogenic transformation, but the underlying mechanisms remain incompletely understood. While no specific treatment option is available for MDS/A...

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Detalles Bibliográficos
Autores principales: Zhang, Fangliang, Chen, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405558/
https://www.ncbi.nlm.nih.gov/pubmed/36009519
http://dx.doi.org/10.3390/biomedicines10081972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405558/
https://www.ncbi.nlm.nih.gov/pubmed/36009519
http://dx.doi.org/10.3390/biomedicines10081972

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