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Internal Ribosome Entry Site (IRES)-Mediated Translation and Its Potential for Novel mRNA-Based Therapy Development

Many conditions can benefit from RNA-based therapies, namely, those targeting internal ribosome entry sites (IRESs) and their regulatory proteins, the IRES trans-acting factors (ITAFs). IRES-mediated translation is an alternative mechanism of translation initiation, known for maintaining protein syn...

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Detalles Bibliográficos
Autores principales:	Marques, Rita, Lacerda, Rafaela, Romão, Luísa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405587/ https://www.ncbi.nlm.nih.gov/pubmed/36009412 http://dx.doi.org/10.3390/biomedicines10081865

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