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Arc Regulates Transcription of Genes for Plasticity, Excitability and Alzheimer’s Disease

The immediate early gene Arc is a master regulator of synaptic function and a critical determinant of memory consolidation. Here, we show that Arc interacts with dynamic chromatin and closely associates with histone markers for active enhancers and transcription in cultured rat hippocampal neurons....

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Detalles Bibliográficos
Autores principales: Leung, How-Wing, Foo, Gabriel, VanDongen, Antonius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405677/
https://www.ncbi.nlm.nih.gov/pubmed/36009494
http://dx.doi.org/10.3390/biomedicines10081946