Downregulating Mitochondrial DNA Polymerase γ in the Muscle Stimulated Autophagy, Apoptosis, and Muscle Aging-Related Phenotypes in Drosophila Adults

Reactive oxygen species, generated as by-products of mitochondrial electron transport, can induce damage to mitochondrial DNA (mtDNA) and proteins. Here, we investigated whether the moderate accumulation of mtDNA damage in adult muscles resulted in accelerated aging-related phenotypes in Drosophila....

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Detalles Bibliográficos
Autores principales: Ozaki, Mika, Le, Tuan Dat, Inoue, Yoshihiro H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405705/
https://www.ncbi.nlm.nih.gov/pubmed/36008999
http://dx.doi.org/10.3390/biom12081105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405705/
https://www.ncbi.nlm.nih.gov/pubmed/36008999
http://dx.doi.org/10.3390/biom12081105

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