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Defect of IL17 Signaling, but Not Centrinone, Inhibits the Development of Psoriasis and Skin Papilloma in Mouse Models

Patients with psoriasis tend to develop skin cancer, and the hyperproliferation of the epidermis is a histopathological hallmark of both psoriasis and cutaneous squamous cell carcinoma (SCC), indicating that they may share pathogenic mechanisms. Interleukin-17 (IL17) stimulates the proliferation of...

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Detalles Bibliográficos
Autores principales: Jin, Ben, Zhang, Yongfeng, Miller, Haiyan D., He, Ling, Ge, Dongxia, Wang, Alun R., You, Zongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405709/
https://www.ncbi.nlm.nih.gov/pubmed/36009523
http://dx.doi.org/10.3390/biomedicines10081976