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The HPV16E7 Affibody as a Novel Potential Therapeutic Agent for Treating Cervical Cancer Is Likely Internalized through Dynamin and Caveolin-1 Dependent Endocytosis

Affibodies targeting intracellular proteins have a great potential to function as ideal therapeutic agents. However, little is known about how the affibodies enter target cells to interact with intracellular target proteins. We have previously developed the HPV16E7 affibody (Z(HPV16E7)384) for HPV16...

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Detalles Bibliográficos
Autores principales: Zhang, Qingyuan, Zhu, Hua, Cui, Zhouying, Li, Yuxiao, Zhuo, Jiaying, Ye, Jingwei, Zhang, Zhihui, Lian, Zheng, Du, Qianqian, Zhao, Kong-Nan, Zhang, Lifang, Jiang, Pengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405713/
https://www.ncbi.nlm.nih.gov/pubmed/36009008
http://dx.doi.org/10.3390/biom12081114