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Lipid Metabolism in Glioblastoma: From De Novo Synthesis to Storage
Glioblastoma (GBM) is the most lethal primary brain tumor. With limited therapeutic options, novel therapies are desperately needed. Recent studies have shown that GBM acquires large amounts of lipids for rapid growth through activation of sterol regulatory element-binding protein 1 (SREBP-1), a mas...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405736/ https://www.ncbi.nlm.nih.gov/pubmed/36009491 http://dx.doi.org/10.3390/biomedicines10081943 |