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Lipid Metabolism in Glioblastoma: From De Novo Synthesis to Storage

Glioblastoma (GBM) is the most lethal primary brain tumor. With limited therapeutic options, novel therapies are desperately needed. Recent studies have shown that GBM acquires large amounts of lipids for rapid growth through activation of sterol regulatory element-binding protein 1 (SREBP-1), a mas...

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Detalles Bibliográficos
Autores principales: Kou, Yongjun, Geng, Feng, Guo, Deliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405736/
https://www.ncbi.nlm.nih.gov/pubmed/36009491
http://dx.doi.org/10.3390/biomedicines10081943