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Single-Cell FISH Analysis Reveals Distinct Shifts in PKM Isoform Populations during Drug Resistance Acquisition

The Warburg effect, i.e., the utilization of glycolysis under aerobic conditions, is recognized as a survival advantage of cancer cells. However, how the glycolytic activity is affected during drug resistance acquisition has not been explored at single-cell resolution. Because the relative ratio of...

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Detalles Bibliográficos
Autores principales: Kim, Seong Ho, Wi, Ji Hun, Gwak, HyeRan, Yang, Eun Gyeong, Kim, So Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405743/
https://www.ncbi.nlm.nih.gov/pubmed/36008976
http://dx.doi.org/10.3390/biom12081082