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Androgen-Induced MIG6 Regulates Phosphorylation of Retinoblastoma Protein and AKT to Counteract Non-Genomic AR Signaling in Prostate Cancer Cells

The bipolar androgen therapy (BAT) includes the treatment of prostate cancer (PCa) patients with supraphysiological androgen level (SAL). Interestingly, SAL induces cell senescence in PCa cell lines as well as ex vivo in tumor samples of patients. The SAL-mediated cell senescence was shown to be and...

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Detalles Bibliográficos
Autores principales: Schomann, Tim, Mirzakhani, Kimia, Kallenbach, Julia, Lu, Jing, Rasa, Seyed Mohammad Mahdi, Neri, Francesco, Baniahmad, Aria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405759/
https://www.ncbi.nlm.nih.gov/pubmed/36008945
http://dx.doi.org/10.3390/biom12081048