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Androgen-Induced MIG6 Regulates Phosphorylation of Retinoblastoma Protein and AKT to Counteract Non-Genomic AR Signaling in Prostate Cancer Cells
The bipolar androgen therapy (BAT) includes the treatment of prostate cancer (PCa) patients with supraphysiological androgen level (SAL). Interestingly, SAL induces cell senescence in PCa cell lines as well as ex vivo in tumor samples of patients. The SAL-mediated cell senescence was shown to be and...
Autores principales: | Schomann, Tim, Mirzakhani, Kimia, Kallenbach, Julia, Lu, Jing, Rasa, Seyed Mohammad Mahdi, Neri, Francesco, Baniahmad, Aria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405759/ https://www.ncbi.nlm.nih.gov/pubmed/36008945 http://dx.doi.org/10.3390/biom12081048 |
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