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Cancer-Associated Fibroblasts: Tumorigenicity and Targeting for Cancer Therapy
SIMPLE SUMMARY: Cancer-associated fibroblasts (CAFs) are found in the tumor microenvironment and exhibit several protumorigenic functions. Preclinical studies suggest that CAFs can be reduced, eliminated, or reprogrammed; however, clinical translation has not yet occurred. A better understanding of...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405783/ https://www.ncbi.nlm.nih.gov/pubmed/36010899 http://dx.doi.org/10.3390/cancers14163906 |