LLL12B, a Novel Small-Molecule STAT3 Inhibitor, Induces Apoptosis and Suppresses Cell Migration and Tumor Growth in Triple-Negative Breast Cancer Cells

Persistent STAT3 signaling plays a pivotal role in human tumor malignancy, including triple-negative breast cancer (TNBC). There are few treatment options currently available for TNBC; thus, given its importance to cancer, STAT3 is a potential cancer therapeutic target and is the focus of drug disco...

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Detalles Bibliográficos
Autores principales: Pan, Li, Chen, Xiang, Rassool, Feyruz Virgilia, Li, Chenglong, Lin, Jiayuh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405793/
https://www.ncbi.nlm.nih.gov/pubmed/36009550
http://dx.doi.org/10.3390/biomedicines10082003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405793/
https://www.ncbi.nlm.nih.gov/pubmed/36009550
http://dx.doi.org/10.3390/biomedicines10082003

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