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LLL12B, a Novel Small-Molecule STAT3 Inhibitor, Induces Apoptosis and Suppresses Cell Migration and Tumor Growth in Triple-Negative Breast Cancer Cells
Persistent STAT3 signaling plays a pivotal role in human tumor malignancy, including triple-negative breast cancer (TNBC). There are few treatment options currently available for TNBC; thus, given its importance to cancer, STAT3 is a potential cancer therapeutic target and is the focus of drug disco...
Autores principales: | Pan, Li, Chen, Xiang, Rassool, Feyruz Virgilia, Li, Chenglong, Lin, Jiayuh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405793/ https://www.ncbi.nlm.nih.gov/pubmed/36009550 http://dx.doi.org/10.3390/biomedicines10082003 |
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