Novel Scaffolds for Modulation of NOD2 Identified by Pharmacophore-Based Virtual Screening

Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is an innate immune pattern recognition receptor responsible for the recognition of bacterial peptidoglycan fragments. Given its central role in the formation of innate and adaptive immune responses, NOD2 represents a valuable tar...

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Detalles Bibliográficos
Autores principales: Guzelj, Samo, Tomašič, Tihomir, Jakopin, Žiga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405794/
https://www.ncbi.nlm.nih.gov/pubmed/36008948
http://dx.doi.org/10.3390/biom12081054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405794/
https://www.ncbi.nlm.nih.gov/pubmed/36008948
http://dx.doi.org/10.3390/biom12081054

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