Thiophosphate Analogs of Coenzyme A and Its Precursors—Synthesis, Stability, and Biomimetic Potential

Coenzyme A (CoA) is ubiquitous and essential for key cellular processes in any living organism. Primary degradation of CoA occurs by enzyme-mediated pyrophosphate hydrolysis intracellularly and extracellularly to form adenosine 3’,5’-diphosphate and 4’-phosphopantetheine (PPanSH). The latter can be...

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Detalles Bibliográficos
Autores principales: Löcherer, Christian, Tosun, Elif, Backes, Hannah, Jäschke, Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405834/
https://www.ncbi.nlm.nih.gov/pubmed/36008959
http://dx.doi.org/10.3390/biom12081065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405834/
https://www.ncbi.nlm.nih.gov/pubmed/36008959
http://dx.doi.org/10.3390/biom12081065

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