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Cocoa Extract Provides Protection against 6-OHDA Toxicity in SH-SY5Y Dopaminergic Neurons by Targeting PERK

Parkinson’s disease (PD) represents one of the most common neurodegenerative disorders, characterized by a dopamine (DA) deficiency in striatal synapses and misfolded toxic α-synuclein aggregates with concomitant cytotoxicity. In this regard, the misfolded proteins accumulation in neurodegenerative...

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Detalles Bibliográficos
Autores principales: Vestuto, Vincenzo, Amodio, Giuseppina, Pepe, Giacomo, Basilicata, Manuela Giovanna, Belvedere, Raffaella, Napolitano, Enza, Guarnieri, Daniela, Pagliara, Valentina, Paladino, Simona, Rodriquez, Manuela, Bertamino, Alessia, Campiglia, Pietro, Remondelli, Paolo, Moltedo, Ornella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405838/
https://www.ncbi.nlm.nih.gov/pubmed/36009556
http://dx.doi.org/10.3390/biomedicines10082009