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BRCA Mutations in Ovarian and Prostate Cancer: Bench to Bedside
SIMPLE SUMMARY: DNA damage is one of the hallmarks of cancer. Epithelial ovarian cancer (EOC) —especially the high-grade serous subtype—harbors a defect in at least one DNA damage response (DDR) pathway. Defective DDR results from a variety of lesions affecting homologous recombination (HR) and nonh...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405840/ https://www.ncbi.nlm.nih.gov/pubmed/36010882 http://dx.doi.org/10.3390/cancers14163888 |