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BRCA Mutations in Ovarian and Prostate Cancer: Bench to Bedside

SIMPLE SUMMARY: DNA damage is one of the hallmarks of cancer. Epithelial ovarian cancer (EOC) —especially the high-grade serous subtype—harbors a defect in at least one DNA damage response (DDR) pathway. Defective DDR results from a variety of lesions affecting homologous recombination (HR) and nonh...

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Detalles Bibliográficos
Autores principales:	Boussios, Stergios, Rassy, Elie, Moschetta, Michele, Ghose, Aruni, Adeleke, Sola, Sanchez, Elisabet, Sheriff, Matin, Chargari, Cyrus, Pavlidis, Nicholas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405840/ https://www.ncbi.nlm.nih.gov/pubmed/36010882 http://dx.doi.org/10.3390/cancers14163888

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