Design, Synthesis and Pharmacological Evaluation of Novel Conformationally Restricted N-arylpiperazine Derivatives Characterized as D(2)/D(3) Receptor Ligands, Candidates for the Treatment of Neurodegenerative Diseases

Most neurodegenerative diseases are multifactorial, and the discovery of several molecular mechanisms related to their pathogenesis is constantly advancing. Dopamine and dopaminergic receptor subtypes are involved in the pathophysiology of several neurological disorders, such as schizophrenia, depre...

Descripción completa

Detalles Bibliográficos
Autores principales: da Silva Cunha, Thayssa Tavares, Silva, Rafaela Ribeiro, Rodrigues, Daniel Alencar, de Sena Murteira Pinheiro, Pedro, Kronenberger, Thales, Sant’Anna, Carlos Maurício R., Noël, François, Fraga, Carlos Alberto Manssour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405847/
https://www.ncbi.nlm.nih.gov/pubmed/36009006
http://dx.doi.org/10.3390/biom12081112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405847/
https://www.ncbi.nlm.nih.gov/pubmed/36009006
http://dx.doi.org/10.3390/biom12081112

Ejemplares similares