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Cisplatin-Induced Kidney Toxicity: Potential Roles of Major NAD(+)-Dependent Enzymes and Plant-Derived Natural Products

Cisplatin is an FDA approved anti-cancer drug that is widely used for the treatment of a variety of solid tumors. However, the severe adverse effects of cisplatin, particularly kidney toxicity, restrict its clinical and medication applications. The major mechanisms of cisplatin-induced renal toxicit...

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Detalles Bibliográficos
Autores principales: Iskander, Amany, Yan, Liang-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405866/
https://www.ncbi.nlm.nih.gov/pubmed/36008971
http://dx.doi.org/10.3390/biom12081078