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FAM107A Inactivation Associated with Promoter Methylation Affects Prostate Cancer Progression through the FAK/PI3K/AKT Pathway

SIMPLE SUMMARY: Prostate cancer (PCa) is a common male malignancy. FAM107A, or actin-associated protein, is commonly downregulated in PCa and is associated with a poor patient prognosis. We investigated the role of FAM107A in PCa and found that downregulation of FAM107A expression was caused by hype...

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Detalles Bibliográficos
Autores principales: Ke, Shuai, Liu, Zelin, Wang, Qinghua, Zhai, Guanzhong, Shao, Haoren, Yu, Xi, Guo, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405870/
https://www.ncbi.nlm.nih.gov/pubmed/36010909
http://dx.doi.org/10.3390/cancers14163915