Anabolic Effects of a Novel Simvastatin Derivative on Treating Rat Bone Defects

Large bone defects may develop fracture nonunion, leading to disability and psychosocial burdens. Bone grafting with anabolic agents is a good autografting alternative. Simvastatin, as a cholesterol-lowering agent worldwide, is proven to enhance osteogenesis. Considering its dose-dependent adverse e...

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Detalles Bibliográficos
Autores principales: Lee, Tien-Ching, Chen, Hui-Ting, Tai, I-Chun, Kao, Li-Ting, Hung, Ming-Hsin, Chen, Chung-Hwan, Fu, Yin-Chih, Wang, Yan-Hsiung, Kao, Chih-Ming, Chang, Je-Ken, Ho, Mei-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405916/
https://www.ncbi.nlm.nih.gov/pubmed/36009462
http://dx.doi.org/10.3390/biomedicines10081915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405916/
https://www.ncbi.nlm.nih.gov/pubmed/36009462
http://dx.doi.org/10.3390/biomedicines10081915

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