A Novel Splice Variant of BCAS1 Inhibits β-Arrestin 2 to Promote the Proliferation and Migration of Glioblastoma Cells, and This Effect Was Blocked by Maackiain

SIMPLE SUMMARY: BCAS1-SV1, a novel splice variant of BCAS1, promotes the proliferation and migration of glioblastoma cells by directly binding to and inhibiting the tumor suppressor function of β-arrestin 2. Maackiain blocks the specific interaction of BCAS1-SV1 with β-arrestin 2 and shows potential...

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Detalles Bibliográficos
Autores principales: Kuo, Yun-Hua, Hung, Huey-Shan, Tsai, Chia-Wen, Chiu, Shao-Chih, Liu, Shih-Ping, Chiang, Yu-Ting, Shyu, Woei-Cherng, Lin, Shinn-Zong, Fu, Ru-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405932/
https://www.ncbi.nlm.nih.gov/pubmed/36010884
http://dx.doi.org/10.3390/cancers14163890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405932/
https://www.ncbi.nlm.nih.gov/pubmed/36010884
http://dx.doi.org/10.3390/cancers14163890

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