Suppression of Cardiogenic Edema with Sodium–Glucose Cotransporter-2 Inhibitors in Heart Failure with Reduced Ejection Fraction: Mechanisms and Insights from Pre-Clinical Studies

In heart failure with reduced ejection fraction (HFrEF), cardiogenic edema develops from impaired cardiac function, pathological remodeling, chronic inflammation, endothelial dysfunction, neurohormonal activation, and altered nitric oxide-related pathways. Pre-clinical HFrEF studies have shown that...

Descripción completa

Detalles Bibliográficos
Autores principales: Sullivan, Ryan D., McCune, Mariana E., Hernandez, Michelle, Reed, Guy L., Gladysheva, Inna P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405937/
https://www.ncbi.nlm.nih.gov/pubmed/36009562
http://dx.doi.org/10.3390/biomedicines10082016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405937/
https://www.ncbi.nlm.nih.gov/pubmed/36009562
http://dx.doi.org/10.3390/biomedicines10082016

Ejemplares similares