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A Drug Screening Reveals Minocycline Hydrochloride as a Therapeutic Option to Prevent Breast Cancer Cells Extravasation across the Blood–Brain Barrier

Among breast cancer (BC) patients, 15–25% develop BC brain metastases (BCBM), a severe condition due to the limited therapeutic options, which points to the need for preventive strategies. We aimed to find a drug able to boost blood–brain barrier (BBB) properties and prevent BC cells (BCCs) extravas...

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Detalles Bibliográficos
Autores principales: Godinho-Pereira, Joana, Lopes, Margarida Dionísio, Garcia, Ana Rita, Botelho, Hugo M., Malhó, Rui, Figueira, Inês, Brito, Maria Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405959/
https://www.ncbi.nlm.nih.gov/pubmed/36009536
http://dx.doi.org/10.3390/biomedicines10081988