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A Drug Screening Reveals Minocycline Hydrochloride as a Therapeutic Option to Prevent Breast Cancer Cells Extravasation across the Blood–Brain Barrier
Among breast cancer (BC) patients, 15–25% develop BC brain metastases (BCBM), a severe condition due to the limited therapeutic options, which points to the need for preventive strategies. We aimed to find a drug able to boost blood–brain barrier (BBB) properties and prevent BC cells (BCCs) extravas...
Autores principales: | Godinho-Pereira, Joana, Lopes, Margarida Dionísio, Garcia, Ana Rita, Botelho, Hugo M., Malhó, Rui, Figueira, Inês, Brito, Maria Alexandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405959/ https://www.ncbi.nlm.nih.gov/pubmed/36009536 http://dx.doi.org/10.3390/biomedicines10081988 |
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