Altered Conformational Landscape upon Sensing Guanine Nucleotides in a Disease Mutant of Elongation Factor-like 1 (EFL1) GTPase

The final maturation step of the 60S ribosomal subunit requires the release of eukaryotic translation initiation factor 6 (human eIF6, yeast Tif6) to enter the pool of mature ribosomes capable of engaging in translation. This process is mediated by the concerted action of the Elongation Factor-like...

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Detalles Bibliográficos
Autores principales: Pérez-Juárez, Jesús, Tapia-Vieyra, Juana Virginia, Gutiérrez-Magdaleno, Gabriel, Sánchez-Puig, Nuria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405973/
https://www.ncbi.nlm.nih.gov/pubmed/36009035
http://dx.doi.org/10.3390/biom12081141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405973/
https://www.ncbi.nlm.nih.gov/pubmed/36009035
http://dx.doi.org/10.3390/biom12081141

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