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DNA Hypomethylation as a Potential Link between Excessive Alcohol Intake and Cardiometabolic Dysfunction in Morbidly Obese Adults

A large percentage of obese patients in the United States suffer a comorbid substance use disorder, mainly alcohol use. Alcohol consumption interferes with the absorption of dietary methyl donors such as folate required for the one-carbon metabolism pathway and subsequently for DNA methylation. In t...

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Detalles Bibliográficos
Autores principales: Mirza, Imaduddin, Naquiallah, Dina, Mohamed, Ariej, Abdulbaseer, Uzma, Hassan, Chandra, Masrur, Mario, Ali, Mohamed M., Phillips, Shane A., Mahmoud, Abeer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406007/
https://www.ncbi.nlm.nih.gov/pubmed/36009501
http://dx.doi.org/10.3390/biomedicines10081954