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DNA Hypomethylation as a Potential Link between Excessive Alcohol Intake and Cardiometabolic Dysfunction in Morbidly Obese Adults
A large percentage of obese patients in the United States suffer a comorbid substance use disorder, mainly alcohol use. Alcohol consumption interferes with the absorption of dietary methyl donors such as folate required for the one-carbon metabolism pathway and subsequently for DNA methylation. In t...
Autores principales: | Mirza, Imaduddin, Naquiallah, Dina, Mohamed, Ariej, Abdulbaseer, Uzma, Hassan, Chandra, Masrur, Mario, Ali, Mohamed M., Phillips, Shane A., Mahmoud, Abeer M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406007/ https://www.ncbi.nlm.nih.gov/pubmed/36009501 http://dx.doi.org/10.3390/biomedicines10081954 |
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