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Design, Synthesis and Activity of New N(1)-Alkyl Tryptophan Functionalized Dendrimeric Peptides against Glioblastoma

Background: Due to resistance to conventional therapy, a blood–brain barrier that results in poor drug delivery, and a high potential for metastasis, glioblastoma (GBM) presents a great medical challenge. Since the repertoire of the possible therapies is very limited, novel therapeutic strategies re...

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Detalles Bibliográficos
Autores principales: Sowińska, Marta, Szeliga, Monika, Morawiak, Maja, Zabłocka, Barbara, Urbanczyk-Lipkowska, Zofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406037/
https://www.ncbi.nlm.nih.gov/pubmed/36009010
http://dx.doi.org/10.3390/biom12081116