Pre-Training on In Vitro and Fine-Tuning on Patient-Derived Data Improves Deep Neural Networks for Anti-Cancer Drug-Sensitivity Prediction

SIMPLE SUMMARY: Cancer cell lines vary greatly from one another because each one underwent a combination of random mutations. Therefore, the effectiveness of anti-cancer drugs also varies across cancer cell lines. In order to understand which drugs are effective against which cancer cells, researche...

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Detalles Bibliográficos
Autores principales: Prasse, Paul, Iversen, Pascal, Lienhard, Matthias, Thedinga, Kristina, Herwig, Ralf, Scheffer, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406038/
https://www.ncbi.nlm.nih.gov/pubmed/36010942
http://dx.doi.org/10.3390/cancers14163950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406038/
https://www.ncbi.nlm.nih.gov/pubmed/36010942
http://dx.doi.org/10.3390/cancers14163950

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