HOXA Amplification Defines a Genetically Distinct Subset of Angiosarcomas

Angiosarcoma is a rare, devastating malignancy with few curative options for disseminated disease. We analyzed a recently published genomic data set of 48 angiosarcomas and noticed recurrent amplifications of HOXA-cluster genes in 33% of patients. HOXA genes are master regulators of embryonic vascul...

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Detalles Bibliográficos
Autores principales: Xie, Hongbo M., Bernt, Kathrin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406048/
https://www.ncbi.nlm.nih.gov/pubmed/36009018
http://dx.doi.org/10.3390/biom12081124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406048/
https://www.ncbi.nlm.nih.gov/pubmed/36009018
http://dx.doi.org/10.3390/biom12081124

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