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HOXA Amplification Defines a Genetically Distinct Subset of Angiosarcomas

Angiosarcoma is a rare, devastating malignancy with few curative options for disseminated disease. We analyzed a recently published genomic data set of 48 angiosarcomas and noticed recurrent amplifications of HOXA-cluster genes in 33% of patients. HOXA genes are master regulators of embryonic vascul...

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Detalles Bibliográficos
Autores principales:	Xie, Hongbo M., Bernt, Kathrin M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406048/ https://www.ncbi.nlm.nih.gov/pubmed/36009018 http://dx.doi.org/10.3390/biom12081124

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