Genomic Aberrations Generate Fusion Gene FOXK2::TP63 and Activate NFKB1 in Cutaneous T-Cell Lymphoma

Cutaneous T-cell lymphoma (CTCL) is a severe lymphoid malignancy with a worse prognosis lacking curative treatment regimens. Several gene mutations and deregulated pathways, including NFkB signaling, have been implicated in its pathogenesis. Accordingly, CTCL cell line HUT-78 reportedly contains mut...

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Detalles Bibliográficos
Autores principales: Nagel, Stefan, Pommerenke, Claudia, Quentmeier, Hilmar, Meyer, Corinna, Kaufmann, Maren, MacLeod, Roderick A. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406051/
https://www.ncbi.nlm.nih.gov/pubmed/36009586
http://dx.doi.org/10.3390/biomedicines10082038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406051/
https://www.ncbi.nlm.nih.gov/pubmed/36009586
http://dx.doi.org/10.3390/biomedicines10082038

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