Ultra Deep Sequencing of Circulating Cell-Free DNA as a Potential Tool for Hepatocellular Carcinoma Management

SIMPLE SUMMARY: In this unicentric prospective study, we analyzed the most prevalent mutations in HCC (TERT promoter, TP53, CTNNB1, AXIN1 and ARID1A) in plasma cfDNA by next-generation sequencing, aiming to elucidate their value as prognostic noninvasive biomarkers. Total cfDNA (cut-off value 2 ng/µ...

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Detalles Bibliográficos
Autores principales: Higuera, Mónica, Vargas-Accarino, Elena, Torrens, María, Gregori, Josep, Salcedo, María Teresa, Martínez-Campreciós, Joan, Torres, Gloria, Bermúdez-Ramos, María, Bilbao, Itxarone, Guerrero-Murillo, Mercedes, Serres-Créixams, Xavier, Merino, Xavier, Rodríguez-Frías, Francisco, Quer, Josep, Mínguez, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406074/
https://www.ncbi.nlm.nih.gov/pubmed/36010868
http://dx.doi.org/10.3390/cancers14163875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406074/
https://www.ncbi.nlm.nih.gov/pubmed/36010868
http://dx.doi.org/10.3390/cancers14163875

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