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Translocation of Distinct Alpha Synuclein Species from the Nucleus to Neuronal Processes during Neuronal Differentiation

Alpha synuclein (aSyn) and its aggregation are crucial for the neurodegeneration of Parkinson’s disease (PD). aSyn was initially described in the nucleus and presynaptic nerve terminals. However, the biology of nuclear aSyn and the link of aSyn between subcellular compartments are less understood. C...

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Detalles Bibliográficos
Autores principales: Pieger, Katharina, Schmitt, Verena, Gauer, Carina, Gießl, Nadja, Prots, Iryna, Winner, Beate, Winkler, Jürgen, Brandstätter, Johann Helmut, Xiang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406079/
https://www.ncbi.nlm.nih.gov/pubmed/36009004
http://dx.doi.org/10.3390/biom12081108