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Blocking Studies to Evaluate Receptor-Specific Radioligand Binding in the CAM Model by PET and MR Imaging

SIMPLE SUMMARY: In the development of new targeted radiopharmaceuticals, it is mandatory to demonstrate their target-specific binding. Rodents are still primarily used for these experiments. With respect to the 3Rs principles, the demand for alternative methods to reduce the number of animal experim...

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Detalles Bibliográficos
Autores principales: Löffler, Jessica, Herrmann, Hendrik, Scheidhauer, Ellen, Wirth, Mareike, Wasserloos, Anne, Solbach, Christoph, Glatting, Gerhard, Beer, Ambros J., Rasche, Volker, Winter, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406147/
https://www.ncbi.nlm.nih.gov/pubmed/36010864
http://dx.doi.org/10.3390/cancers14163870