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Blocking Studies to Evaluate Receptor-Specific Radioligand Binding in the CAM Model by PET and MR Imaging
SIMPLE SUMMARY: In the development of new targeted radiopharmaceuticals, it is mandatory to demonstrate their target-specific binding. Rodents are still primarily used for these experiments. With respect to the 3Rs principles, the demand for alternative methods to reduce the number of animal experim...
Autores principales: | Löffler, Jessica, Herrmann, Hendrik, Scheidhauer, Ellen, Wirth, Mareike, Wasserloos, Anne, Solbach, Christoph, Glatting, Gerhard, Beer, Ambros J., Rasche, Volker, Winter, Gordon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406147/ https://www.ncbi.nlm.nih.gov/pubmed/36010864 http://dx.doi.org/10.3390/cancers14163870 |
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