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Circulating Low Density Neutrophils Are Associated with Resistance to First Line Anti-PD1/PDL1 Immunotherapy in Non-Small Cell Lung Cancer

SIMPLE SUMMARY: Immunotherapy has been positioned as frontline therapy for advanced non-small cell lung cancer (NSCLC), alone when PD-L1 tumor expression is high, or combined with chemotherapy otherwise. However, 50% of the patients do not respond to the treatment and the mechanisms of resistance ar...

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Detalles Bibliográficos
Autores principales: Arasanz, Hugo, Bocanegra, Ana Isabel, Morilla, Idoia, Fernández-Irigoyen, Joaquín, Martínez-Aguillo, Maite, Teijeira, Lucía, Garnica, Maider, Blanco, Ester, Chocarro, Luisa, Ausin, Karina, Zuazo, Miren, Fernández-Hinojal, Gonzalo, Echaide, Miriam, Fernández-Rubio, Leticia, Piñeiro-Hermida, Sergio, Ramos, Pablo, Mezquita, Laura, Escors, David, Vera, Ruth, Kochan, Grazyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406164/
https://www.ncbi.nlm.nih.gov/pubmed/36010840
http://dx.doi.org/10.3390/cancers14163846